Professor Pačes is engaged in genomics. His research group was one of the first to completely sequence a genome, namely DNA of a bacterial virus. In addition, he discovered a specific enzyme involved in the catabolism of the plant hormone cytokinine. He is the co-author of the first Czech synthetic gene (for the precursor of the neurotransmitter enkefaline). He has published more than 100 original papers and is the co-author, editor and translator of five books. His papers have been cited more than 900 times. He lectures on molecular genetics and gene engineering at the Institute of Chemical Technology in Prague. He was the supervisor for ten PhD students. Repeatedly, he has been elected chairman of the Czech Society for Biochemistry and Molecular Biology. He is a founding member of the Learned Society of the Czech Republic, was elected a member of the European Academy of Sciences and Arts and of the prestigious European Molecular Biology Organisation (EMBO). He is chairman of the Commission for Conferring the Degree of DrSc. in the fields of biochemistry, biophysics and molecular biology. He is a member of Scientific Councils of Charles University, the Institute of Chemical Technology in Prague and its Faculty of Food and Biochemical Technology. He was associated with Yale University, the University of Chicago, and did research at Universities in Seville and in Bristol. He worked at the Institute of Applied Biochemistry in Japan and lectured at several institutions abroad. He is the editor of the international journal Research in Microbiology and a member of editorial boards of European Journal of Biochemistry and Chemické listy (Chemical papers). He regularly popularises his field of research for the public. He organised the First European Conference of the ESF, "Functional Genomics and Disease" (2003, Prague), and he co-organised the World Biochemical Congress (1988, Prague). He organised a course on DNA sequencing at the University of Seville (1988) and participated in organising courses for the Federation of European Biochemical Societies (FEBS) entitled "Sequence and Microinjection of DNA" (1993, 1994, 1995, 1996, 1997 and 2004, Prague).
In 1989, he was awarded the State Prize for Science, and he received the Award of the Czechoslovak Academy of Sciences and that of the Academy of Sciences of the Czech Republic for the promotion of science. During the years 1993-1997 he was Vice-President of the Academy of Sciences of the Czech Republic. He was Director of the Institute of Molecular Genetics of the ASCR (1999-2005). At the XXVI Session of the Academy Assembly held on 24 March 2005, he was elected President of the Academy of Sciences of the Czech Republic. |
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